Formal report writing Essay Example | Topics and Well Written Essays - 1250 words

Formal report writing - Essay Example within the firm to identify the core activities which are to be carried out by the senior staff, while the secondary functions are assigned another organization that may provide such functions to the company at affordable. Interstate, Inc is a New York based company, which specializes in providing domestic insurance for private individuals and corporations. It is considering moving all or part of its 150 person call centre to an oversee location in order to reduce its operating cost. The call centre currently handles calls of operating agents and enquiries from members of the public from USA. Management groups are researching about different countries in order to evaluate their potential to host a pilot project which should be operational within six months. If successful the centre will take over the full accountability for all call centre operations within 12 months. The management team will be meeting later to present their recommendations. Outsourcing is a management practice of taking a function of an organization to be managed by another organization on behalf of the company. InterState Inc, may hand over the secondary functions that can be handled by other specialized organizations on its behalf so that the core staff of InterState may concentrate on the most important functions (Lacity & Joseph, 12). The outsourced services are offered within the country or state and employees of the company whose services are outsourced performs the function and are paid for the services rendered. Through outsourcing InterState might be able to avoid many costs like payment of retirement benefits to employees, payments to employees who are on leave, or when the employees are less productive. Outsourcing has therefore become cheaper in the end because the company avoids certain costs (Haugen, Susan & Kacy, 24). Off shoring on the other hand is a business management practice in which a company like InterState may take moves its activities to another location in another

Clinical trials for intiviral in general Essay Example | Topics and Well Written Essays - 500 words

Clinical trials for intiviral in general - Essay Example After the promising drug has been identified based on its mode of action on the target , it undergoes a thorough pre-clinical testing involving biological test-tube and animal studies. The primary goal is to determine the safety of the product for initial use in humans, and if the drug shows pharmacological activity that justifies commercial development. These studies will show if the test drug works against its viral target. In the case of HIV, after it was reported that diketo acids can inhibit strand transfer step (3), studies were used to exhibit the disease progression and test treatments in macaque monkeys (4). Animal studies have utilized the simian immunodeficiency virus (SIV) to study acquired immunodeficiency in primates, however, SIV shares only 50% homology to HIV. Recently, a genetically altered HIV can infect rhesus monkeys in such a way that the resulting infection mimics the early stages of HIV human infection (5). Successful pre-clinical trials pave the way for a drug company to file an Investigational New Drug application. The application will include data on animal pharmacology and toxicological studies, manufacturing information, the protocols for the clinical trials, and the information about the investigators. The investigators and sponsors are responsible for the protection of the clinical trial subjects (6). Drugs have to be subjected to several phase of clinical trials for them to be approved for marketing. Phase I trials are meant to determine the metabolic and pharmacological actions, and the maximum tolerable dose of the drug in 20 to 80 volunteers. The trial normally lasts for a minimum of one month to a year. Measured outcomes are vital signs, virus plasma and serum levels and adverse events or reactions to the drug. Trials are unblinded and do not employ controls (7), although blinding and controls can be used to improve the validity. Phase I trials usually do not have therapeutic objectives, and may be conducted in